The Improvement of Urethral Function in the Rat Stress Urinary Incontinence Model by Electrical Stimulation Combined With Pelvic Floor Muscle Training To Activate VEGF and ERK 1/2

To explore the effect of electrical stimulation combined with pelvic floor muscle training on improvement urethral function in rats stress urinary incontinence and to further study its possible mechanism. 48 were randomly divided into blank control group, model treatment group group. The rehabilitation was treated after successful modeling. sneeze test, urodynamics strength measurement used detect rat urethra function. expressions vascular endothelial growth factor extracellular-signal-regulated kinase 1/2 genes tissue cells detected by reverse transcription-polymerase chain reaction. urodynamics, measurement, microvessel count histopathology results showed that successfully constructed could significantly reduce incidence rate improve strength, number capillaries repair damaged vaginal nerves. Reverse transcription–polymerase reaction analysis treatment, extracellularsignal- regulated up-regulated up-regulation more obvious Electrical effectively action mechanism may be related activation extracellular regulatory protein extracellular-signalregulated 1/2.